Deep Learning Mengutamakan Relevansi Kontekstual

Deep learning dalam pembelajaran adalah pendekatan yang menekankan pemahaman mendalam dan keterkaitan dengan konteks nyata. Relevansi kontekstual menjadi esensial karena membantu siswa menghubungkan teori yang dipelajari dengan aplikasi di kehidupan sehari-hari. Hal ini selaras dengan pandangan Ki Hajar Dewantara yang menekankan pentingnya pendidikan berpusat pada kebutuhan dan pengalaman siswa (Siregar, 2020).

Pendekatan ini sejalan dengan Kurikulum Merdeka, yang mendorong pembelajaran berbasis proyek (project-based learning) untuk menumbuhkan keterampilan berpikir kritis dan relevansi dalam dunia nyata. Menurut penelitian Fadillah (2021), pembelajaran berbasis konteks membuat siswa lebih antusias dan mampu memahami materi dengan lebih baik, terutama dalam mata pelajaran yang sering dianggap abstrak, seperti matematika atau sains. Sebagai contoh, pembelajaran konsep pecahan dapat diintegrasikan dengan kegiatan berbagi makanan, sehingga siswa memahami bahwa pecahan adalah bagian dari pengalaman sehari-hari.

Relevansi kontekstual juga mendukung pembelajaran sepanjang hayat (lifelong learning). Ketika siswa belajar melalui konteks yang relevan, mereka tidak hanya memahami materi, tetapi juga mampu mengaplikasikan pengetahuan tersebut dalam situasi lain (Rahmawati & Wahyudi, 2023). Pendekatan ini membangun keterampilan abad ke-21 yang meliputi komunikasi, kolaborasi, kreativitas, dan pemecahan masalah.

Dengan demikian, relevansi kontekstual dalam deep learning sangat penting untuk menciptakan pembelajaran yang bermakna, aplikatif, dan mampu membentuk siswa menjadi individu yang siap menghadapi tantangan dunia nyata.

Referensi:

Fadillah, M. (2021). Penerapan Project-Based Learning dalam Pembelajaran Matematika di Sekolah Dasar. Jurnal Pendidikan Dasar, 12(2), 101-115.
Rahmawati, I., & Wahyudi, A. (2023). Relevansi Kontekstual dalam Pembelajaran Berbasis Kurikulum Merdeka. Jurnal Inovasi Pendidikan, 19(1), 45-57.
Siregar, A. M. (2020). Pendidikan Berbasis Karakter: Perspektif Pemikiran Ki Hajar Dewantara. Jurnal Pendidikan Nasional, 7(3), 23-29.

Read also  Mengedepankan Evaluasi Proses dalam Deep Learning untuk Pembelajaran Bermakna

This Post Has 54 Comments

  1. luvbet August 25, 2025 Reply

    A luvbet é confiável, galera? Já ouvi falar bem, mas queria saber a opinião de vocês antes de colocar meu dinheiro lá. Alguém já sacou dinheiro de boa?

  33. available at Valley`s website October 1, 2025 Reply

    Anavar For Women Side Effects, Benefits, Before & After

    ### 1. Why Calcium & Magnesium Matter
    | Nutrient | Key Biological Functions | What Happens When It’s Low |
    |———-|————————-|—————————|
    | **Calcium (Ca)** | • Builds and maintains bone & tooth structure.

    • Transmits nerve impulses, contracts muscles, and
    activates blood‑coagulation proteins. | • Osteoporosis /
    bone pain.
    • Muscle cramps or spasms.
    • Abnormal heart rhythm. |
    | **Magnesium (Mg)** | • Co‑factor for ~300 enzymes that synthesize DNA,
    ATP, proteins and neurotransmitters.
    • Helps relax smooth & cardiac muscle, regulates blood glucose, and stabilizes cellular membranes.
    | • Fatigue, irritability, restless legs.
    • Muscle twitches, cramps, or spasms.
    • Low blood sugar; impaired insulin sensitivity.

    |

    **Key insight:**
    Both minerals are essential for **muscle tone, heart rhythm and
    energy production**—and they work together.
    Magnesium is a natural *magnesium‑dependent* enzyme that maintains the body’s
    **electrolyte balance** (Na⁺/K⁺ gradients) that keeps cells from becoming overstimulated or dehydrated.

    —

    ## 2. Why Your Body “Cries Out” for Electrolytes

    ### a. Sodium & Water Balance
    – **Sodium** is the main extracellular ion that attracts water.
    When sodium levels drop, plasma volume shrinks → blood pressure
    falls, and the body attempts to restore it.

    – A drop in sodium (or loss of salt through sweat) triggers thirst, increased salt
    appetite, and sometimes a feeling of “dryness” or irritability.

    ### b. Potassium & Muscle Contraction
    – **Potassium** is the key intracellular ion for muscle contraction, especially cardiac muscle.
    Low potassium leads to weakness, cramps, and palpitations.

    – High potassium (hyperkalemia) can cause dangerous
    heart rhythms. Both extremes disturb normal cell membrane potentials.

    ### c. Calcium’s Role in Signaling
    – While calcium is low in blood relative to other ions, it’s crucial for intracellular signaling pathways that regulate muscle contraction,
    neurotransmitter release, and bone mineralization.
    – Hypocalcemia triggers tetany (involuntary spasms),
    whereas hypercalcemia can cause lethargy and
    constipation.

    —

    ## 3. How the Body Regulates Calcium Levels

    ### A. Hormonal Control
    | Hormone | Primary Source | Target Organ(s) | Main Action |
    |———|—————–|—————–|————-|
    | Parathyroid hormone (PTH) | Parathyroid glands | Bone, kidney, intestine | ↑ bone resorption, ↑ renal calcium reabsorption, ↑ calcitriol synthesis
    |
    | Calcitonin | Thyroid C-cells | Bone, kidney | ↓ bone resorption, ↑ urinary excretion of Ca²⁺
    |
    | 1‑α‑Hydroxylated vitamin D (calcitriol) | Kidney (PTH stimulated) | Intestine, bone | ↑ intestinal absorption of Ca²⁺/PO₄³⁻ |

    **Key points**

    * Low serum calcium → ↑ PTH.
    * PTH increases bone resorption and renal reabsorption; it also
    stimulates production of calcitriol which in turn boosts intestinal uptake of calcium and phosphate.

    * Calcitonin acts oppositely to PTH, lowering plasma calcium by inhibiting osteoclasts.

    —

    ### 3. **Bone remodeling – osteoblast vs osteoclast**

    | Cell | Origin | Key factor(s) stimulating | Main function |
    |——|——–|—————————|—————|
    | **Osteoclast** | Multinucleated from monocyte‑macrophage lineage | RANKL (from osteoblasts/osteocytes), M-CSF, PTH → ↑RANKL | Bone resorption; releases Ca²⁺ &
    PO₄³⁻ |
    | **Osteoblast** | Mesenchymal stem cell → pre‑osteoblast → osteoblast | BMPs, Wnt/β‑catenin, IGFs,
    thyroid hormone, PTH (via 1α,25(OH)₂D) | Bone formation; mineralizes matrix |

    **PTH effects**
    – ↑RANKL: stimulates resorption.
    – ↑1α-hydroxylase in kidney → more active vitamin D → ↑intestinal Ca²⁺ absorption.

    —

    ## 3. Why the “calcium–phosphate paradox” is hard to explain

    | Factor | Effect on calcium | Effect on phosphate |
    |——–|——————-|———————|
    | **PTH** | ↓ bone, ↑ kidney excretion, ↑ GI via vitamin D → *net increase* | ↑ bone resorption,
    ↑ urinary excretion, ↑ GI absorption → *net increase* |
    | **Vitamin D (calcitriol)** | ↑ intestinal absorption of Ca²⁺ |
    ↑ intestinal absorption of PO₄³⁻ → *increases both* |
    | **Low phosphate diet** | ↓ serum PO₄³⁻ | ↓ serum PO₄³⁻, may
    decrease PTH, but Ca²⁺ unaffected (depends on absorption) |

    Because vitamin D increases the absorption of both calcium and phosphate
    from the gut simultaneously, any dietary or hormonal intervention that raises
    calcium will almost inevitably raise phosphate as well.

    The only way to separate them is by **restricting dietary phosphate** (low‑phosphate diet or using phosphate binders),
    which reduces serum phosphate but leaves calcium homeostasis largely
    intact if vitamin D and calcium intake are adequate.

    Hence, in a low‑phosphate diet, calcium can be increased through
    supplementation or adequate vitamin D without a corresponding rise in serum
    phosphate.
    If the diet is not controlled for phosphate, increasing calcium (e.g., via supplementation) will normally also raise serum phosphate because both minerals share absorption pathways and regulatory mechanisms.

    **Answer:**

    **The best way to increase calcium intake without affecting phosphate levels is to supplement
    with calcium alone while simultaneously restricting dietary phosphate consumption. This approach ensures a net rise in calcium without the usual accompanying increase in phosphate that can occur when calcium supplements are taken with high-phosphate foods
    or drinks.**

    —

    ### 1. Why calcium supplements raise serum phosphate

    | **Mechanism** | **What happens?** |
    |—————|——————-|
    | **Calcium‑phosphate equilibrium** | Calcium and phosphate bind to
    form a soluble complex in the gut; excess calcium can shift this balance, increasing phosphate absorption. |
    | **Hormonal response (PTH)** | Higher intestinal calcium triggers parathyroid hormone release, which boosts renal reabsorption of calcium
    but also increases bone resorption, releasing more phosphate into circulation. |
    | **Compensatory kidney action** | The kidneys excrete excess
    calcium but retain phosphate to maintain ionic balance.
    |

    **Result:** Serum phosphate rises unless countered.

    —

    ### How to keep phosphate low while taking calcium

    1. **Choose a calcium source with low natural phosphate**
    – **Aluminum hydroxide or magnesium hydroxide (often used in antacids)** are
    calcium salts that contain almost no phosphate.
    – If you prefer oral supplements, look for **calcium carbonate
    tablets labeled “phosphate‑free”**.

    2. **Use a buffering agent to improve absorption without adding phosphate**
    – **Magnesium oxide or magnesium citrate** can be taken with calcium; they
    enhance solubility and reduce the chance of precipitation that would
    otherwise release phosphate.

    3. **Limit high‑phosphate foods around dosing times**
    – Avoid dairy, nuts, seeds, and processed meats during the window when you take
    your supplement.

    4. **Monitor urinary composition regularly**
    – Keep a log of any symptoms (e.g., flank pain, swelling).
    If there’s any suspicion of stone formation or edema, contact your healthcare
    provider immediately.

    5. **Consider periodic imaging if risk factors are high**
    – For patients with recurrent stones or family history,
    baseline ultrasound or CT scans can be useful to rule out existing calculi before starting therapy.

    —

    ## Bottom‑Line Takeaway

    – **Sodium oxalate is a powerful pro‑stone
    agent**; its use should be avoided in people prone to calcium oxalate stone formation.
    – **Urinary supersaturation** is the key mechanism: high oxalate +
    calcium → calcium oxalate crystals → stones or deposits.

    – **Monitoring** (urine chemistry, imaging) and **adjusting therapy** are essential if sodium oxalate must be used.

    – **Patient education** on hydration, diet, and symptom vigilance can mitigate risks.

    By understanding the underlying biochemistry and implementing vigilant monitoring, clinicians can reduce the risk of stone formation or tissue deposition when using sodium oxalate therapeutically.

    References:

    available at Valley`s website

  49. sermorelin ipamorelin blend side effects October 6, 2025 Reply

    Ipamorelin is a synthetic growth hormone releasing peptide
    that has gained popularity among athletes and bodybuilders for its potential to stimulate natural growth hormone production. While
    it offers certain benefits, users—especially women—must be aware of
    possible side effects that can arise from its use.
    Understanding these risks, monitoring symptoms, and consulting healthcare professionals
    are essential steps for anyone considering sermorelin ipamorelin blend side effects.

    Ipamorelin Side Effects: What You Need to Know – A Comprehensive Guide

    1. Hormonal Imbalances

    Because ipamorelin prompts the pituitary gland to
    release growth hormone (GH) and insulin-like growth factor 1 (IGF‑1), it can disturb the natural hormonal equilibrium in women. This may lead to irregular
    menstrual cycles, spotting, or amenorrhea (the absence of periods).

    In some cases, an overproduction of GH could trigger a temporary increase
    in prolactin levels, which might also affect menstrual regularity.

    2. Water Retention and Edema

    Growth hormone can cause fluid retention as
    it influences sodium reabsorption in the kidneys. Women who are sensitive to water retention may notice
    puffiness around the eyes, hands, or feet, especially during the first few weeks of use.
    This swelling is generally mild but can be uncomfortable.

    3. Increased Appetite and Weight Gain

    A rise in GH levels often boosts appetite. Users might experience
    an increased desire for calories, leading to weight gain if dietary habits are not adjusted.
    For women who already struggle with maintaining a healthy weight, this side effect could pose additional challenges.

    4. Joint and Muscle Pain

    Some users report mild aches or stiffness in joints and muscles after beginning ipamorelin therapy.
    The pain tends to be diffuse rather than localized and often improves as the body
    adapts to the new hormonal environment. However, persistent
    discomfort warrants medical evaluation.

    5. Carpal Tunnel Syndrome Symptoms

    Elevated GH can increase tissue swelling around nerves, potentially exacerbating or triggering carpal tunnel
    syndrome symptoms such as tingling, numbness, or pain in the hands and wrists.
    Women who already experience these sensations should monitor changes closely.

    6. Sleep Disturbances

    Growth hormone is predominantly secreted during deep sleep
    stages. While ipamorelin can enhance GH release, it may also interfere with normal sleep architecture for some
    users, leading to insomnia or disrupted sleep patterns.
    Adequate hydration and a balanced bedtime routine can help mitigate these effects.

    7. Hormonal Mood Changes

    Fluctuations in estrogen, progesterone, and other hormones can influence mood.
    Some women report mild anxiety, irritability, or mood swings during the first weeks of ipamorelin use.
    These changes are typically transient but may require counseling or
    therapy if they become severe.

    8. Rare but Serious Side Effects

    Acromegaly-like Symptoms: Prolonged excessive GH release can theoretically lead to acromegaly, characterized
    by bone overgrowth and organ enlargement. This is exceedingly rare with therapeutic doses but remains a theoretical
    risk.

    Allergic Reactions: Though uncommon, some individuals may develop injection site reactions such as redness, itching, or swelling.

    Systemic allergic responses are extremely rare.

    9. Interactions With Other Medications

    Ipamorelin can interact with medications that affect hormone
    levels or the pituitary gland, such as estrogen therapy, birth control pills, or thyroid
    hormones. Women on these treatments should discuss
    potential interactions with their healthcare provider before starting
    ipamorelin.

    10. Monitoring and Mitigation Strategies

    Track Menstrual Cycle: Keep a log of cycle changes; irregularities warrant
    medical evaluation.

    Maintain Hydration: Adequate water intake can help reduce fluid retention.

    Adjust Diet: Consider a balanced diet to counter increased appetite.

    Exercise Moderately: Regular, moderate exercise supports hormonal balance
    and helps manage weight.

    Seek Medical Advice Early: If side effects become bothersome or persist beyond a few weeks,
    consult a clinician.

    Book a Call

    If you’re considering ipamorelin but have questions about how it might affect your body—or if you’ve experienced
    any of the side effects mentioned above—booking a call with a qualified healthcare professional can provide personalized guidance.
    During the conversation, you’ll be able to discuss:

    Your current health status and medication history.

    The appropriate dosage and administration schedule
    for your goals.

    Monitoring protocols to track potential side effects.

    Alternative strategies if ipamorelin proves unsuitable.

    A professional appointment offers peace of mind by ensuring that any decision regarding ipamorelin use is grounded in medical evidence and tailored to
    your unique circumstances.

    Common Ipamorelin Side Effects

    Below is a concise list of the most frequently reported side effects, particularly relevant for women:

    Menstrual irregularities – spotting or missed periods.

    Water retention – mild swelling in extremities.

    Increased appetite – leading to potential weight gain.

    Joint and muscle discomfort – diffuse aches that ease
    over time.

    Carpal tunnel-like symptoms – tingling or numbness in hands.

    Sleep disruptions – difficulty falling or staying asleep.

    Mood fluctuations – irritability or mild anxiety.

    Injection site reactions – redness, itching, or swelling.

    Rare allergic responses – severe systemic reactions are extremely uncommon.

    Potential long-term hormonal changes – rare risk of excessive GH
    effects.

    By staying informed about these side effects and maintaining open communication with healthcare
    providers, women can make educated decisions regarding ipamorelin usage while minimizing potential risks.

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